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Hamilton

Guides for Hamilton liquid handlers — VENUS methods, labware definitions, and protocol porting.

All Tecan Hamilton Hamilton STAR Protocol Scripting Protocol Optimisation Dead Volume QA & Validation Venus Scripting
File Import, Export, and Advanced Venus Scripting: Connecting Your Method to the Outside World

Worktable, teaching, sequences, and step logic give you control over the deck. File I/O, Shell, and parallel execution connect the method to everything outside it.

Dead Volume in Hamilton Reagent Reservoirs: What You're Leaving Behind and Why It Matters

Dead volume in flat-bottom Hamilton reservoirs is geometry-driven and calculable — here's how to get the number right and avoid run failures.

Dead Volume in Microplates: Geometry, Accuracy, and Why Your Wells Are Never Quite Empty

Dead volume in microplates is a per-well, per-transfer problem at the 5-500 µL scale — here's how plate format and tip selection change the calculation.

Tecan vs. Hamilton: Why Protocol Scripting Looks So Different Between Platforms

A breakdown of how EVOware and VENUS diverge in scripting philosophy, and what that means for teams porting protocols between instruments.

Variables, Calculations, and Loops: Making Your Venus Method Flexible

A static script does one thing one way every time. Variables, calculations, and loops are what turn it into a method that adapts at runtime.

Single Steps, Power Steps, and Smart Steps: Choosing the Right Tool for the Job

Smart Steps look simplest, Single Steps look most complete — the right choice depends on what the step actually needs to do.

Hamilton vs Tecan Troughs: A Dead Volume Comparison

Hamilton flat-bottom and Tecan tapered troughs make different geometric trade-offs that produce meaningfully different dead volume profiles — here's how to choose and migrate between them.

Sequences in Venus: The Logic Underneath Every Pipetting Step

Every aspirate and dispense step in Venus references a sequence — understanding pointer behaviour and ordering is the biggest step toward writing methods deliberately.

Teaching Your Deck: Why a Correct Definition Is Not the Same as a Correct Position

A perfect worktable model isn't enough — teaching is the calibration step that confirms the software model matches your specific physical deck.

The Venus Worktable: Why You Build the Deck Before You Write a Single Step

Open Venus and the instinct is to start scripting. The worktable comes first — here's what it contains and why nothing else works without it.